Developments in neuroimaging: positron emission tomography.
Identifieur interne : 000B01 ( Main/Exploration ); précédent : 000B00; suivant : 000B02Developments in neuroimaging: positron emission tomography.
Auteurs : A Jon Stoessl [Canada]Source :
- Parkinsonism & related disorders [ 1873-5126 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- complications : Parkinson Disease.
- diagnosis : Parkinson Disease.
- diagnostic imaging : Brain.
- Humans, Positron-Emission Tomography.
Abstract
Positron emission tomography (PET) is a powerful technique to quantitatively assess brain function in vivo. In Parkinson's disease (PD), PET can assist in the identification of dopamine deficiency, the characterization of dopamine and other neurotransmitter receptors and transporters, serve as a biomarker and provide insights into motor and non-motor complications of PD. PET can also shed light on mechanisms that underlie disease, such as aberrant protein deposition and neuroinflammation. Emerging developments in multimodal imaging offer the opportunity to study multiple questions concurrently and offer great promise for the future.
DOI: 10.1016/S1353-8020(13)70042-7
PubMed: 24262176
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Positron emission tomography (PET) is a powerful technique to quantitatively assess brain function in vivo. In Parkinson's disease (PD), PET can assist in the identification of dopamine deficiency, the characterization of dopamine and other neurotransmitter receptors and transporters, serve as a biomarker and provide insights into motor and non-motor complications of PD. PET can also shed light on mechanisms that underlie disease, such as aberrant protein deposition and neuroinflammation. Emerging developments in multimodal imaging offer the opportunity to study multiple questions concurrently and offer great promise for the future.</div>
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